Aaron Sams, PhD
Aaron J. Sams, PhD is a Director of Research and Scientific Product Development at Embark. A broadly trained evolutionary biologist, he is passionate about working with Embark’s scientists to analyze genetic data from Embark’s customers to understand the distribution of genetic variation in canines and how genetic and environmental variation underpins disease in dogs.
Prior to joining Embark, his research applied computational methods to better understand the evolutionary dynamics of ancient human population admixture and the evolution of complex traits, such as immune-related disease in humans. He is thrilled to be applying those skills to advance our understanding of canine genomics and health and build useful products for Embark’s customers.
Dr. Sams is a graduate of the University of Tennessee-Knoxville and received both an MS and PhD in Biological Anthropology from the University of Wisconsin-Madison. Subsequently, he worked as a Postdoctoral Fellow in Biological Statistics and Computational Biology at Cornell University.
All work
Measuring Inbreeding and How Genetic COI Can Help Your Breeding Program
Learn about genetic COI (coefficient of inbreeding) and how it can be used to inform breeding decisions with Aaron Sams, PhD. Many factors are considered when choosing which dogs to use in breeding programs including conformation, temperament, genetic disease mutations, and much more. Assessing the impact of inbreeding is another factor to consider. In this...
How DNA Genotyping Works
Occasionally, we get questions from customers curious about how their dog’s DNA is processed into the genotype data that we analyze to understand breed ancestry and health risks. Once we receive your dog’s cheek swab, the DNA contained in the sample is copied many times in a process called amplification. Next, all of those copies...
Why Mixed Breed Siblings May Not Look Exactly Alike
“Are these dogs really siblings? They look nothing alike.” This is a common question people have after using our relative finder. After you’ve Embarked your pup, there is a chance that you’ll come across dogs that are very closely related to yours but look very different. We’ve written previously about how the breed(s) in your...
Breeding for the future: Why genome-wide diversity matters
Many dog breeders have reached out to us to ask “What makes Embark’s test better for maintaining diversity and lowering disease risk in my breed?” Specifically, they are often interested in how Embark compares to other diversity management products that use a very small number of genetic markers to make breeding recommendations. In short, you...
VIDEO: Inbreeding Explained
When closely related dogs mate, it is defined as inbreeding. “Inbreeding is the mating of individuals or organisms that are genetically closely related, resulting in increased homozygosity and consequently an increase in the occurrence of recessive traits,” according to Nature. “This can lead to inbreeding depression: reduced biological fitness of the population.” In this video,...
Embark Discovers Why Dogs Have Blue Eyes
At Embark, we are working to end preventable disease in dogs. Today, we are proud to officially announce the first step along that path to discovery, our first published scientific research! So, what did we find? In short, we discovered a genetic mutation, specifically a duplication of DNA sequence near ALX4 (a gene on dog...
A Tail of Two Breeds: How Dog DNA Diverges Over Time
At Embark, we often receive questions like this one: “How can you differentiate ancestry between closely related breeds?” For example, American Bulldogs and modern English Bulldogs are the descendants of working English Bulldogs that made their way to America with working-class immigrants. So, how can we tell the difference between the genetics of American Bulldogs...
Embarking on Dog Ancestry Research
If you have Embarked your dog and opted to participate in scientific research, you’re officially a citizen scientist! On behalf of Embark, I want to say thanks for your contribution. In 2017, Embark presented some of the first research to come out of the data that you and others have given us. We were at...
