Alanine Aminotransferase Activity

Dogs do not show any outward signs when they have this clinical trait.

Genetic testing is the only way to provide your veterinarian with this clinical tool.

Veterinarians may recommend blood work to establish a baseline ALT value for healthy dogs with one or two copies of this variant.

Talk to your vet about your dog's ALT result, as it may help them better interpret your dog's blood work.

Dogs with this result do not exhibit symptoms or develop health issues associated with this variant.

This genetic test can be used as a clinical tool by veterinarians. Veterinarians reference a range of laboratory values when deciding if a dog's ALT level is normal. Dogs with one or two copies of this variant have an ALT value that is low or on the low end of the normal reference range. Vets can use this test to determine the significance of an increased ALT value.

Penetrance: Dogs with one or two copies of this variant will have an ALT level that is either low or on the low end of the normal range even when they are completely healthy and their liver function is normal.

Gene

GPT

Inheritance type

codominant

Clinical category

Clinical

Citations

1. White et al 2016