This is a Neuromuscular condition.

Congenital Myasthenic Syndrome, CMS

What is Congenital Myasthenic Syndrome, CMS?

This is a disease characterized by episodes of severe exercise intolerance and weakness.

What are the signs & symptoms that develop in affected dogs?

Affected puppies can usually play or run for up to a half hour, after which their strides get progressively shorter and the dog collapses. After resting, the puppy appears normal again.

When do signs and symptoms develop?

Signs first appear in puppies, typically starting at 6 weeks of age.

How do vets diagnose this condition?

Genetic testing, blood work, neurological tests, and clinical signs can be used to diagnose this condition.

How is this condition treated?

CMS is a lifelong condition and affected puppies may become refractory to medication used to help treat the acquired form of this condition.

What actions should I take if my dog is affected?

  • Minimizing intense exercise may help reduce clinical signs. Please follow the recommendations from your veterinarian.
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