Darier Disease
Darier Disease is a skin condition that causes crusted areas, cyst formation, and other abnormalities.
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Signs and symptoms
Affected dogs may have well-defined areas of crusting or ulceration within their ears and/or cysts (nodules) anywhere on their skin. These lesions can be both painful and itchy.
This disease is typically diagnosed in puppies, often before the age of six months. -
Diagnosis
A combination of clinical signs, genetic testing, and skin biopsy can be used to diagnose Darier Disease.
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Treatment
Darier Disease can be challenging to treat. Antibiotics can be used when secondary infections are present. Surgery may be performed to remove the cysts (nodules). Laser therapy can be used to manage the lesions in the ears.
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What to do if your dog is at risk
Actions
- Please follow your veterinarian's treatment recommendations and carefully monitor any lumps or lesions in the ears.
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Genetic Information
This variant was first described in the Irish Terrier.
This variant is inherited in an autosomal dominant manner, meaning that a dog with either one or two copies of the variant can show signs of Darier Disease.
Gene names:
ATP2A2 Intron 14 ‐ chr
Inheritance type:
dominant
Citations:
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Breeds affected
This health condition affects the following breeds
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