Early Bilateral Deafness
Hearing loss can be categorized into three groups: age-related, congenital (hearing loss present at birth), and early-onset (neonatally or during puppy or early adulthood). Causes of hearing loss are diverse, with a complex interaction of genetic and environmental components correlated with specific genes. The bilateral form of hearing loss due to this variant in the LOXHD1 gene occurs early in a dog's life. It is supposed that LOXHD1 has an essential role in maintaining normal inner ear (cochlear) hair cell function.
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Signs and symptoms
You may notice your dog no longer responding to sounds like clapping, knocking, doorbells, or the vacuum. The dog may appear to become less obedient by no longer responding to verbal commands or their name. They may bark excessively or become difficult to wake.
Deafness is often noted beginning at four to five months of age. However, owners may observe hearing impairment beginning at a few weeks of age. It is uncertain if this form of hearing loss is early-onset or congenital.Uncover health risks with Embark
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Diagnosis
Veterinarians can diagnose hearing disorders by using brainstem auditory-evoked response (BAER) testing to confirm unilateral or bilateral deafness.
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Treatment
There are no widespread treatments. Management is aimed at lifestyle changes, training, and reducing the risk of injury.
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What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s deafness result so you can discuss any changes in hearing and plan care as needed.
- Train your dog using visual cues or hand signals instead of verbal commands.
- Avoid startling your dog by approaching gently and using vibration or light to get their attention.
- Make sure your dog’s collar or leash has tags noting that they are deaf to help others interact safely and respectfully.
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Genetic Information
This variant was first identified in Rottweilers.
This variant has an autosomal recessive inheritance, meaning that dogs must have two copies of the variant in order to show clinical signs of Early Bilateral Deafness from it.
Gene names:
LOXHD1 Exon 38 ‐ chr
Inheritance type:
recessive
Citations:
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Breeds affected
This health condition affects the following breeds
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