Ehlers Danlos

Affected puppies have very elastic and stretchy skin and hyper-mobile joints. They are injury prone and skin can be severely torn following even minor injuries.

Signs are first recognized in puppies.

Genetic testing, clinical signs, and skin biopsy can all be used to diagnose this condition.

Unfortunately, there is no treatment for this condition.

Talk to your vet about your dog’s Ehlers-Danlos syndrome result so you can plan appropriate care and monitoring.

Handle your dog gently and avoid rough play or activities that could lead to cuts or bruises, such as dog parks, outdoor hikes, or running through dense brush.

Keep their environment safe by padding sharp edges, using soft bedding, and preventing jumping from high surfaces.

If wounds occur, seek veterinary attention promptly, as the skin may be slow to heal or tear easily.

This mutation was first described in a Doberman.

Penetrance: This mutation has an autosomal recessive inheritance, meaning that dogs must have two copies of the mutation in order to show clinical signs.

Gene

ADAMTS2

Inheritance type

recessive

Clinical category

Integument

Citations

1. Jaffey et al 2019

• Doberman Pinscher