Pachyonychia Congenita
A disorder of skin maturation, this condition can cause especially thick, hardened footpads that are prone to cracking.
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Signs and symptoms
Painful thickening of the footpads is the first sign most owner's recognize.
This is often first recognized in juvenile dogs. -
Diagnosis
Clinical signs, genetic testing, and biopsy can be used to diagnose this condition.
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Treatment
Cracks in the foot pads make dogs more likely to contract a secondary bacterial infection, which can be managed with appropriate antibiotics; treatment of the foot pads with softening soaks can also reduce pain associated with the condition.
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What to do if your dog is at risk
Actions
- Give medications as directed and follow your veterinarian's advice.
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Genetic Information
It has been mapped to the KRT16 gene in the Dogue de Bordeaux.
This mutation has an autosomal recessive inheritance, meaning that dogs must have two copies of the mutation in order to show clinical signs.
Gene names:
KRT16 (Exon 6) ‐ chr
Inheritance type:
recessive
Citations:
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Breeds affected
This health condition affects the following breeds
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