Integument

This is a Skin & Connective Tissues condition.

Pachyonychia Congenita

What is Pachyonychia Congenita?

A disorder of skin maturation, this condition can cause especially thick, hardened footpads that are prone to cracking. It has been mapped to the KRT16 gene in the Dogue de Bordeaux. Cracks in the foot pads make dogs more likely to contract a secondary bacterial infection, which can be managed with appropriate antibiotics; treatment of the foot pads with softening soaks can also reduce pain associated with the condition.

What are the signs & symptoms that develop in affected dogs?

Painful thickening of the footpads is the first sign most owner's recognize.

When do signs and symptoms develop?

This is often first recognized in juvenile dogs.

How do vets diagnose this condition?

Clinical signs, genetic testing, and biopsy can be used to diagnose this condition.

How is this condition treated?

Cracks in the foot pads make dogs more likely to contract a secondary bacterial infection, which can be managed with appropriate antibiotics; treatment of the foot pads with softening soaks can also reduce pain associated with the condition.

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