Hereditary Nasal Parakeratosis, HNPK

skin & connective tissue

This condition causes the skin of the nose to be overly thick and shingle-like, which can be uncomfortable for your dog.

  • Signs and symptoms

    HNPK isn't usually as upsetting to the dog as it is to the owner, but can be quite painful if the thickened flakes of skin are abruptly removed--so no picking.

    This is often first recognized in juvenile dogs.

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  • Diagnosis

    Clinical signs, genetic testing, and biopsy can be used to diagnose this condition.

  • Treatment

    This condition can be managed with softening soaks and gentle exfoliation.

  • What to do if your dog is at risk


    • Treat your dog's nose gently and follow your veterinarian's advice.

  • Genetic Information

    This mutation was first described in the Labrador Retriever.

    This mutation has an autosomal recessive inheritance, meaning that dogs must have two copies of the mutation in order to show clinical signs.

    Gene names:

    SUV39H2 ‐ chr

    Inheritance type:


  • Breeds affected

    This health condition affects the following breeds

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