This is a Metabolic condition.

Hypocatalasia, Acatalasemia

What is Hypocatalasia, Acatalasemia?

Catalase is important in fighting reactive oxygen species, which can cause cellular damage. Fortunately, many enzymes can break down reactive oxygen species; as such acatalasemia is usually a benign disease: however, some acatalasemic dogs suffer from what is known as Takahara’s disease, where patients have progressive mouth ulcers.

What are the signs & symptoms that develop in affected dogs?

Most dogs show no clinical signs of this disease. Affected dogs can have oral ulcers and difficulty eating.

When do signs and symptoms develop?

This condition is most often diagnosed in adulthood.

How do vets diagnose this condition?

This condition is diagnosed through genetic testing. Oral disease can be diagnosed during a complete physical examination by your veterinarian. Some dogs require sedation for an oral exam due to pain.

How is this condition treated?

No treatment is required unless mouth ulcerations are present. Ulcerations cause an increased susceptibility to oral infections, which must be monitored closely. Treatment options include regular dental care, judicious use of antibiotics, and soothing mouth sprays and rinses.

What actions should I take if my dog is affected?

  • Please follow your veterinarian's advice to maintain your dog's dental health.
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