Inflammatory Myopathy
This inflammatory muscle condition causes significant muscle weakness and loss of muscle mass. Affected dogs may have difficulty with normal movement and daily activities.
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Signs and symptoms
Signs include weakness, gait changes, and muscle atrophy.
Signs first appear at 3-9 months of age.Uncover health risks with Embark
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Diagnosis
Genetic testing, clinical signs, and muscle biopsy can be used to diagnose this disorder.
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Treatment
There is no treatment currently for this disorder. In the study affected dogs were euthanized by two years of age due to the profound muscle weakness.
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What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s inflammatory myopathy result so you can plan appropriate care and monitoring.
- Watch for signs such as stiffness, weakness, or reluctance to exercise, and contact your vet if you notice these changes.
- Provide regular, gentle activity to help maintain mobility and prevent muscle loss.
- A calm environment, good traction, and supportive care can help keep your dog comfortable day to day.
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Genetic Information
This mutation was first described in the Dutch Shepherd.
This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
Gene names:
SLC25A12 ‐ chr
Inheritance type:
recessive
Citations:
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Breeds affected
This health condition affects the following breeds
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