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Neurologic

This is a Brain and Spinal Cord condition.

Leonberger Polyneuropathy 2

What is LPN2?

Named for the Leonberger dog, LPN2 is a non-painful neurodegenerative condition leading to gradual muscle atrophy. This can cause signs of weakness, laryngeal paralysis, and difficulty breathing; affected dogs often develop signs as young adults. LPN2 has been compared to the human condition Charcot-Marie-Tooth Disease.

What are the signs & symptoms that develop in affected dogs?

This can cause signs of weakness, laryngeal paralysis, and difficulty breathing. Dogs affected as young adults will often have more severe signs.

When do signs and symptoms develop?

Development of signs is widely variable, from several months to 11 years of age.

How do vets diagnose this condition?

Unless a genetic basis is suspected due to the age, breed, or history of the dog, diagnostics must be performed to rule out infectious, inflammatory, or neoplastic causes.

How is this condition treated?

There is no treatment for this disorder. Certain medications may be prescribed to control symptoms.

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