Ligneous Membranitis, LM
This is a rare condition that causes chronic inflammation of delicate tissues like the nose, mouth, throat, and eyelids. Over time, scarring can develop and, in some cases, the heart or nervous system may also be affected.
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Signs and symptoms
Affected dogs often have chronic nasal discharge, conjunctivitis, and coughing.
Signs typically develop in puppies.Uncover health risks with Embark
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Diagnosis
Genetic and laboratory testing along with clinical signs are used to diagnose this disease.
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Treatment
LM is a devastating disease and requires aggressive and continuous replacement of plasminogen with medically available blood products. Euthanasia is often elected.
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What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s ligneous membranitis result, as it may influence how they approach diagnostics and monitor your dog’s health over time.
- Schedule regular checkups and let your vet know right away if you notice any signs such as eye irritation, discharge, or changes in your dog’s mouth or breathing.
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Genetic Information
This mutation was first described in the Scottish Terrier.
This disease is inherited in an autosomal recessive manner, meaning that a dog must have two copies of the mutation to be affected.
Gene names:
PLG ‐ chr
Inheritance type:
recessive
Citations:
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Breeds affected
This health condition affects the following breeds
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