Lundehund Syndrome
Norwegian Lundehunds are known to have stomach and intestinal problems collectively known as Lundehund Syndrome. This genetic mutation affects neuroendocrine cells in the intestinal tract and is thought to be similar to inflammatory bowel disease.
-
Signs and symptoms
Affected dogs will have moderate to severe clinical signs including vomiting, diarrhea, weight loss, and hair loss. Fluid retention in the legs (edema) and fluid in the abdomen (ascites) can also be seen.
Signs can first appear in a wide range of ages - from approximately 2 to 10 years of age. -
Diagnosis
Genetic testing, blood work, abdominal ultrasound, and surgical biopsy are all used to diagnose this condition.
-
Treatment
At this time, treatment is symptomatic. In very severe cases with a poor response to therapy, euthanasia is considered.
-
What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s Lundehund syndrome result so you can plan an appropriate diet and regular monitoring.
- Follow your vet’s nutritional recommendations closely, as special diets can help manage digestive symptoms and nutrient absorption.
- Watch for signs such as diarrhea, vomiting, weight loss, or loss of appetite, and contact your vet if you notice these.
- With consistent care and monitoring, many dogs with this condition can live relatively normal, comfortable lives.
-
Genetic Information
This mutation was first described in Norwegian Lundehunds.
This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
Gene names:
LEPREL1 ‐ chr
Inheritance type:
recessive
Citations:
-
Breeds affected
This health condition affects the following breeds
Learn about your dog’s unique genetic health
Dog owners
Breed identification, health and trait insights, personalized care recommendations, and the world’s first canine relative finder—all in one leading dog DNA test.
Learn about the report for dog ownersShop the test
Breeding programs
Embark’s test for breeding programs is one comprehensive DNA test designed with your needs in mind.
Learn about the report for breedersShop the test
