Lundehund Syndrome
Norwegian Lundehunds are known to have stomach and intestinal problems collectively known as Lundehund Syndrome. This genetic mutation affects neuroendocrine cells in the intestinal tract and is thought to be similar to inflammatory bowel disease.
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Signs and symptoms
Affected dogs will have moderate to severe clinical signs including vomiting, diarrhea, weight loss, and hair loss. Fluid retention in the legs (edema) and fluid in the abdomen (ascites) can also be seen.
Signs can first appear in a wide range of ages - from approximately 2 to 10 years of age. -
Diagnosis
Genetic testing, blood work, abdominal ultrasound, and surgical biopsy are all used to diagnose this condition.
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Treatment
At this time, treatment is symptomatic. In very severe cases with a poor response to therapy, euthanasia is considered.
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What to do if your dog is at risk
Actions
- Please consult your veterinarian for dietary advice, therapeutic prescriptions and periodic monitoring.
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Genetic Information
This mutation was first described in Norwegian Lundehunds.
This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
Gene names:
LEPREL1 ‐ chr
Inheritance type:
recessive
Citations:
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Breeds affected
This health condition affects the following breeds
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