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Gastrointestinal

This is a Gastrointestinal condition.

Lundehund Syndrome

What is Lundehund Syndrome?

Norwegian Lundehunds are known to have stomach and intestinal problems collectively known as Lundehund Syndrome. This genetic mutation affects neuroendocrine cells in the intestinal tract and is thought to be similar to inflammatory bowel disease. This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs. Signs can first appear in a wide range of ages - from approximately 2 to 10 years of age. Affected dogs will have moderate to severe clinical signs including vomiting, diarrhea, weight loss, and hair loss. Fluid retention in the legs (edema) and fluid in the abdomen (ascites) can also be seen. Genetic testing, blood work, abdominal ultrasound, and surgical biopsy are all used to diagnose this condition. At this time, treatment is symptomatic. In very severe cases with a poor response to therapy, euthanasia is considered. Please consult your veterinarian for dietary advice, therapeutic prescriptions and periodic monitoring.

What are the signs & symptoms that develop in affected dogs?

Affected dogs will have moderate to severe clinical signs including vomiting, diarrhea, weight loss, and hair loss. Fluid retention in the legs (edema) and fluid in the abdomen (ascites) can also be seen.

When do signs and symptoms develop?

Signs can first appear in a wide range of ages - from approximately 2 to 10 years of age.

How do vets diagnose this condition?

Genetic testing, blood work, abdominal ultrasound, and surgical biopsy are all used to diagnose this condition.

How is this condition treated?

At this time, treatment is symptomatic. In very severe cases with a poor response to therapy, euthanasia is considered.

What actions should I take if my dog is affected?

Please consult your veterinarian for dietary advice, therapeutic prescriptions and periodic monitoring.

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