Macular Corneal Dystrophy, MCD


This condition causes abnormal corneal accumulation of complex carbohydrates called glycosaminoglycans. The cornea is the surface of the eye.

  • Signs and symptoms

    You will notice the surface of your dog's eyes becoming cloudy. They may or may not have trouble with vision: bumping into walls, hesitant on steps, and cautious in unfamiliar locations.

    This is a disease of middle aged dogs.

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  • Diagnosis

    Veterinarians perform a complete ocular exam and also genetic testing to diagnose this condition.

  • Treatment

    Currently there is no cure for canine MCD, though in humans, a corneal transplant is the gold standard of treatment.

  • What to do if your dog is at risk


    • Carefully monitor your dog's vision.
    • With blind dogs, keeping furniture in the same location, making sure they are on a leash in unfamiliar territory, and training them to understand verbal commands are some of the ways to help them at home.

  • Genetic Information

    This mutation was first described in the Labrador Retriever.

    This mutation is inherited in an autosomal recessive manner; that is, a dog requires two copies of the mutation to show signs of the disease.

    Gene names:

    CHST6 ‐ chr

    Inheritance type:


  • Breeds affected

    This health condition affects the following breeds

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