Methemoglobinemia
Methemoglobinemia is a blood disorder where too much methemoglobin is present. This protein affects how the blood carries oxygen, meaning that the body does not have enough oxygen supply.
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Signs and symptoms
Your dog may have a rapid respiratory rate, blue gums, and exercise intolerance.
Signs of methemoglobinemia often first appear with an associated disease, such as a respiratory infection. -
Diagnosis
Genetic and laboratory testing can be used to diagnose this condition. Please note that there are also toxins that can cause this condition.
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Treatment
Methylene blue can be administered to control the clinical signs. However, this is a long-term therapy, not a cure. Treatment of concurrent infections or inflammation is also recommended.
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What to do if your dog is at risk
Actions
- Please see your veterinarian as soon as possible if you suspect a respiratory infection or any other breathing difficulties, as these can become life-threatening if not addressed.
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Genetic Information
This variant was first described in the Pit Bull Terrier.
This variant is inherited in an autosomal dominant manner, meaning that a dog only requires one copy of the variant to show clinical signs of methemoglobinemia.
Gene names:
CYB5R3 Exon 7 ‐ chr
Inheritance type:
dominant
Citations:
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Breeds affected
This health condition affects the following breeds
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