Methemoglobinemia
Methemoglobinemia is a blood disorder where too much methemoglobin is present. This protein affects how the blood carries oxygen, meaning that the body does not have enough oxygen supply.
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Signs and symptoms
Your dog may have a rapid respiratory rate, blue gums, and exercise intolerance.
Signs of methemoglobinemia often first appear with an associated disease, such as a respiratory infection.Uncover health risks with Embark
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Diagnosis
Genetic and laboratory testing can be used to diagnose this condition. Please note that there are also toxins that can cause this condition.
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Treatment
Methylene blue can be administered to control the clinical signs. However, this is a long-term therapy, not a cure. Treatment of concurrent infections or inflammation is also recommended.
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What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s methemoglobinemia result, as it may influence their choice of medications or anesthesia.
- Most dogs with this result do not show symptoms, but some may be more sensitive to certain drugs or oxygen-related stress.
- Watch for signs of breathing difficulty, fatigue, or bluish gums, and contact your vet right away if you notice any of these symptoms.
- Seek veterinary care promptly if your dog has a respiratory infection or any condition that affects oxygen levels.
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Genetic Information
This variant was first described in the Pit Bull Terrier.
This variant is inherited in an autosomal dominant manner, meaning that a dog only requires one copy of the variant to show clinical signs of methemoglobinemia.
Gene names:
CYB5R3 Exon 7 ‐ chr
Inheritance type:
dominant
Citations:
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Breeds affected
This health condition affects the following breeds
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