Myasthenia Gravis-Like Syndrome
This condition causes progressive muscle weakness that worsens with activity. Puppies may seem stronger in the morning but become increasingly tired or weak by evening, sometimes displaying decreased reflexes or collapsing.
-
Signs and symptoms
Affected puppies had poor coordination, decreased reflexes and collapse.
Signs first appear in young puppies. -
Diagnosis
Genetic testing, blood work, neurological tests, and clinical signs can be used to diagnose this condition.
-
Treatment
This is a lifelong condition that showed poor response to medical treatments.
-
What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s myasthenia gravis–like syndrome result so you can plan appropriate monitoring and care.
- Avoid known triggers such as overexertion, stress, or excitement, which can worsen muscle weakness.
- Watch for signs like a drooping head, difficulty walking, or changes in swallowing, and contact your vet if you notice them.
- With consistent management and a calm, predictable routine, many dogs with this condition can remain comfortable and active.
-
Genetic Information
This mutation was first described in the Heideterrier.
This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
Gene names:
CHRNE ‐ chr
Inheritance type:
recessive
Citations:
-
Breeds affected
This health condition affects the following breeds
Learn about your dog’s unique genetic health
Dog owners
Breed identification, health and trait insights, personalized care recommendations, and the world’s first canine relative finder—all in one leading dog DNA test.
Learn about the report for dog ownersShop the test
Breeding programs
Embark’s test for breeding programs is one comprehensive DNA test designed with your needs in mind.
Learn about the report for breedersShop the test
