Hematologic

This is a Blood condition.

Prekallikrein Deficiency

What is Prekallikrein Deficiency?

This is a benign blood disorder characterized by low levels of prekallikrein; affected dogs typically suffer no ill effects. Prekallikrein is an enzyme necessary for activation of other clotting proteins. Affected dogs have abnormally long clotting times on laboratory coagulation tests, but do not have bleeding tendencies as in other coagulopathies.

What are the signs & symptoms that develop in affected dogs?

Affected dogs have abnormally long clotting times on laboratory coagulation tests, but this does not lead to an increased bleeding risk clinically.

When do signs and symptoms develop?

Dogs are born with this disorder, but it is often not recognized unless your veterinarian performs certain blood tests.

How do vets diagnose this condition?

Genetic testing and laboratory clotting times are used to diagnose this condition.

How is this condition treated?

At this time, no treatment is required for dogs with this genetic mutation.

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