Primary Ciliary Dyskinesia, PCD
This disorder affects the function of tiny moving structures on cells that help clear the airways and support fertility. As a result, affected dogs may be prone to respiratory infections and, in males, reduced fertility.
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Signs and symptoms
This disease can cause increased susceptibility to respiratory infections and, in male dogs, reduced fertility or infertility.
Respiratory infections can develop at anytime, however, male fertility can only be assessed after puberty.Uncover health risks with Embark
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Diagnosis
Genetic and laboratory testing are used to diagnose this condition.
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Treatment
There is no cure for PCD. Respiratory infections need to be treated promptly with the correct antibiotic.
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What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s PCD result so you can work together to plan ongoing care and monitoring.
- Work closely with your vet to prevent and manage respiratory infections through regular checkups and prompt care if your dog becomes ill.
- Watch for signs of infection such as coughing, nasal discharge, or increased effort when breathing, and contact your vet if you notice any of these symptoms.
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Genetic Information
This mutation was first described in the Alaskan Malamute.
This mutation is inherited in an autosomal recessive manner; that is, a dog requires two copies of the mutation to show signs of the disease.
Gene names:
NME5 ‐ chr
Inheritance type:
recessive
Citations:
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Breeds affected
This health condition affects the following breeds
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