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Multisystem

This is a Multisystem condition.

Primary Ciliary Dyskinesia, PCD

What is Primary Ciliary Dyskinesia, PCD?

PCD arises from a mutation that inhibits the function of motile cellular appendages such as sperm flagella and the cilia of respiratory tract cells. These appendages whip with directionality, allowing sperm to propel themselves towards an egg, and for respiratory tract cells to whip dust, bacteria, and mucus up towards the throat to be coughed out.

What are the signs & symptoms that develop in affected dogs?

This disease can cause increased susceptibility to respiratory infections and, in male dogs, reduced fertility or infertility.

When do signs and symptoms develop?

Respiratory infections can develop at anytime, however, male fertility can only be assessed after puberty.

How do vets diagnose this condition?

Genetic and laboratory testing are used to diagnose this condition.

How is this condition treated?

There is no cure for PCD. Respiratory infections need to be treated promptly with the correct antibiotic.

What actions should I take if my dog is affected?

  • Carefully monitor your dog for signs of infection, including: coughing, nasal discharge, and increased respiratory effort.