Primary Open Angle Glaucoma and Primary Lens Luxation

eye

Glaucoma is the result of high intraocular pressure, and if left untreated, can lead to pain and vision loss. The "angle" of primary open glaucoma (POAG) refers to the intersection of the cornea and the iris: this is where aqueous humor (clear fluid filling the eye) must flow to exit the eye. In open angle glaucoma, the iridocorneal angle remains unchanged, and other factors contribute to increased resistance to outflow.

  • Signs and symptoms

    Symptoms can appear suddenly and quite dramatically. Affected dogs’ pupils may be abnormally dilated and the vessels on the surface of the eye may appear engorged. Your dog may also be averse to bright light, shake their head, or paw at their eyes.

    Glaucoma has an adult onset.

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  • Diagnosis

    Veterinarians perform a complete ocular exam and use a device to measure the intraocular pressure of the eye to diagnosis glaucoma. At risk dogs are often tested at their yearly exam.

  • Treatment

    With early diagnosis, glaucoma can be managed with a variety of medical and surgical options. In severe end-stage cases, surgical removal of the affected eyes may be indicated.

  • What to do if your dog is at risk

    Actions

    • Talk to your vet about your dog’s POAG result so you can work together to plan regular eye exams and monitoring.
    • Early detection and treatment are key to preserving vision, so schedule veterinary eye exams as recommended.
    • Glaucoma often starts in one eye, so your vet may recommend preventive treatment for the other eye to help protect vision.
    • Watch for eye changes such as cloudiness, redness, squinting, or pawing at the eye, and contact your vet right away if you notice any of these signs.

  • Genetic Information

    This mutation was first described in the Chinese Shar Pei.

    This mutation is inherited in an autosomal recessive manner; that is, a dog requires two copies of the mutation to show signs of the disease.

    Gene names:

    ADAMTS17 ‐ chr

    Inheritance type:

    recessive

  • Breeds affected

    This health condition affects the following breeds

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