Cardiomyopathy and Juvenile Mortality

Heart

This condition is characterized by an enlarged heart with degenerative changes leading to sudden death at 6-8 weeks of age.

  • Signs and symptoms

    Signs include vomiting, difficulty breathing, pale gum color, twitching/seizures, and sudden death.

    Signs are often first noted at 6-8 weeks of age.

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  • Diagnosis

    Genetic testing and clinical signs can be used to diagnose this condition.

  • Treatment

    There is no treatment for this disorder.

  • What to do if your dog is at risk

    Actions

    • Talk to your vet about your dog’s cardiomyopathy and juvenile mortality result so you can plan appropriate monitoring and care.
    • Signs such as weakness, difficulty breathing, or collapse may appear early in life and can worsen quickly.
    • Focus on keeping your puppy comfortable in a calm environment and avoid strenuous activity.
    • This condition is severe and often rapidly progressive, but providing comfort and stability can help maintain your puppy’s well-being.

  • Genetic Information

    This mutation was first described in the Belgian Shepherd.

    This disease is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.

    Gene names:

    YARS2 ‐ chr

    Inheritance type:

    recessive

  • Breeds affected

    This health condition affects the following breeds

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