Dental-Skeletal-Retinal Anomaly

Skeletal

Dental-Skeletal-Retinal Anomaly (DSRA) is a type of skeletal abnormality affecting the teeth, eyes, and growth of affected dogs.

  • Signs and symptoms

    Affected dogs are smaller than their littermates, with short and angularly bent limbs. Their puppy teeth are translucent and easily break. Their adult teeth can be discolored pink or brown with defects in the enamel. As they age, their vision worsens

    Signs can first be recognized in puppies.

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  • Diagnosis

    A complete physical examination, including an oral exam, is needed to assess any changes in the limbs and teeth. Diagnosis of any vision changes requires an eye exam to visualize the retina.

  • Treatment

    Currently, DSRA cannot be treated, only managed.

  • What to do if your dog is at risk

    Actions

    • Talk to your vet about your dog’s dental skeletal retinal anomaly result so you can discuss any vision or dental changes and plan appropriate monitoring.
    • Dogs with this condition may have reduced vision, so use verbal cues and a consistent routine to help them navigate safely.
    • Practice regular dental care, including brushing your dog's teeth with dog-safe toothpaste, and schedule periodic dental checkups to maintain your dog's oral health.

  • Genetic Information

    This variant was first described in the Cane Corso.

    This variant is inherited in an autosomal recessive manner, meaning that a dog requires two copies of the variant to show signs of DSRA.

    Gene names:

    MIA3 Intron 9 ‐ chr

    Inheritance type:

    recessive

  • Breeds affected

    This health condition affects the following breeds

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