Factor VII Deficiency
This condition affects blood clotting, but symptoms are often mild. Some dogs may bruise or bleed more easily than expected, while many never show any noticeable signs at all.
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Signs and symptoms
Affected dogs bruise easily and can excessively bleed from small wounds. Affected puppies may bleed excessively from their mouth when teething. A subset of dogs that test positive for Factor VII deficiency appear perfectly normal.
This disease is typically diagnosed in puppies or young adults when they are spayed or neutered and have a problem with clotting. However, it can be diagnosed at any age.Uncover health risks with Embark
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Diagnosis
Factor VII deficiency is diagnosed through genetic testing and blood testing at a laboratory. Veterinarians may also nick a dog’s lip with a sterile needle and time how long it takes for clotting to occur.
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Treatment
Factor VII deficiency cannot be treated, only managed.
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What to do if your dog is at risk
Actions
- Talk to your vet about your dog’s Factor VII Deficiency result before any surgeries or dental procedures, as it may influence how they prepare.
- Many dogs with this result never show symptoms or develop health problems related to this variant.
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Genetic Information
Factor VII deficiency is inherited in an autosomal recessive manner, meaning that affected dogs must have two copies of the mutation to show clinical signs.
Gene names:
F7 Exon 5 ‐ chr
Inheritance type:
recessive
Citations:
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Breeds affected
This health condition affects the following breeds
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