Ichthyosis, ICH2

skin & connective tissue

This skin disorder gets its name from the thick, darkly pigmented scales of skin ("ichthys" is Greek for "fish") that affected dogs display over most areas of the body, not including the head or extremities.

  • Signs and symptoms

    Ichthyotic dogs typically have large, greasy dandruff flakes, but are not itchy. They often have discoloration of the skin, especially on the abdomen.

    As puppies, affected dogs can show signs of scaling. These symptoms can worsen as the dog ages or wax and wane throughout the dog's life.

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  • Diagnosis

    Examining the characteristic lesions is the first step in diagnosing Ichthyosis. Confirmatory genetic testing and/or skin biopsies can also be performed.

  • Treatment

    There is no definitive treatment for ichthyosis: typically, ichthyotic dogs are maintained on continuous treatment of mild anti-dandruff shampoos and moisturizing rinses. This is often a chronic and frustrating condition to manage.

  • What to do if your dog is at risk


    • Following your veterinarian's advice on skin care and nutrition is the best way to manage ichthyosis.

  • Genetic Information

    This variant was first identified in Golden Retrievers.

    This variant has an autosomal recessive inheritance, meaning that dogs must have two copies of the variant to show clinical signs of Ichthyosis.

    Gene names:

    ABHD5 Exon 7 ‐ chr

    Inheritance type:


  • Breeds affected

    This health condition affects the following breeds

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