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Multisystem

This is a Multisystem condition.

Renal Cystadenocarcinoma and Nodular Dermatofibrosis

What is RCND?

Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis (RCND) is a multiorgan syndrome that creates dense collagen nodules in the skin and causes cancer in the kidneys and uterus.

What are the signs & symptoms that develop in affected dogs?

Signs of this disease include thick skin nodules, excessive thirst and urination, uterine tumors (leiomyomas) in females, and kidney tumors (renal cystadenocarcinoma). If the cancer metastasizes to the lungs, affected dogs can have respiratory distress.

When do signs and symptoms develop?

First signs usually develop around 5 years of age, with death from the disease likely around 9 years of age.

How do vets diagnose this condition?

Genetic and laboratory testing are used to diagnose this condition. Abdominal ultrasound is used to visualize the uterus.

How is this condition treated?

There is no treatment for RCND. Certain medications, fluid therapy, and surgical management may be recommended.

What actions should I take if my dog is affected?

  • Focus on palliative therapies to increase your dog's comfort and quality of life.