The AKC Canine Health Foundation (AKC CHF) and the Orthopedic Foundations for Animals (OFA) published the Review of the Current State of Genetic Testing – A Living Resource in 2020. It is an extremely useful guide for both novice and long-time breeders.
Not only does it provide practical explanations of genetics and scientific testing methods used, but it also highlights how breeders can benefit from using genetic testing and apply the results to improve the health of their breeding programs. While the report does not cite individual test providers and can be viewed as an independent guide for breeders, we were thrilled to see many of the best practices Embark offers our customers highlighted in the report.
Important among these is Embark’s commitment to providing expert advice and support to breeders on how to apply the test results to their breeding programs. While many providers stop at simply providing test results, Embark’s in-house team of veterinary geneticists advise breeders about the effect genetic COI can have on litter sizes, the complexities of coat colors, and more.
Take a look at a few of the report’s observations excerpted below—and see how Embark stacks up.
Ensuring accuracy of test results: primary source transparency
“Scientific papers are often written using extensive scientific jargon and can be difficult to understand—so it is not uncommon for authors to overextend their findings in the lay summary. It is, thus, important to review the entire paper and not only rely on a lay summary.”
How Embark stacks up
As a science-first company, Embark provides research citations for all our health results (and direct links to view the research, whenever possible) so breeders can confirm breed-relevance and more. Our veterinary geneticists are also available to explain test results and how they can be applied.
Data ownership and sharing
“Some direct-to-consumer testing providers utilize test results in research projects, and indicate that the owners will receive the full SNP data derived from the large panel testing, which then allows owners to share their dog’s genetic data with researchers conducting important studies.”
How Embark stacks up
This is what Embark provides to all customers. Unlike other dog DNA companies, Embark generates research-ready data from every DNA swab, and freely provides it to customers along with ownership of their dog’s data. This data can be leveraged by Embark for new research (often in partnership with Cornell University College of Veterinary Medicine), and customers can also share it with any other organizations of their choosing (researchers, breed clubs, etc.).
Embark for Breeders dog DNA test kits
- Sale Price
- $119-$149 per test
DNA testing data in action: research discoveries for dogs
“Direct-to-consumer testing providers can mine the data derived from owners purchasing DNA testing to discover new genetic variants. For example, a mutation responsible for blue eye color in Siberian Huskies was found using direct-to-consumer testing data.”
How Embark stacks up
Embark is proud that our discovery of the blue-eyed color mutation in Siberian Huskies is highlighted in the report, and this is just one of many findings achieved by our team. The Embark test generates data that provides the basis for future groundbreaking research, and this contributes to the continual additions of new health conditions and traits test included in our Embark for Breeders kit.
Complex disease testing capability is on the horizon for Embark
“Broad-range SNP panels may still be used in the future… with a focus on providing genomic estimated breeding values to assess the likelihood of a dog passing on particular complex traits to its puppies. However, this will require a great many dogs with comprehensive phenotyping across varied environments and across breeds to obtain the accuracy in prediction necessary before such tests can be deployed.”
How Embark stacks up
Embark offers the broad-range SNP panel and research-grade testing platform required to develop the multiple-gene tests that will enable us to better understand, and hopefully one day predict, risk factors for complex diseases like cancer. To support these efforts, every customer can complete the free surveys on their dogs’ Embark profiles.
Navigating the DNA testing landscape can be challenging—but the better you understand it, the more confident breeding decisions you can make. The AKC CHF and OFA sponsored report was prepared by experts from UC Davis and Clemson University and you can read the full report here. As always, feel free to contact our Embark experts with any questions: We’re always glad to help.
