What are the signs & symptoms that develop in affected dogs?
MDR1 often presents in young adulthood, only because this is most commonly when a dog is first exposed to a problem drug like high dose ivermectin or acepromazine.
When do signs and symptoms develop?
Symptoms arise after a dog has received an MDR1 problem drug or dosage, and can range from vomiting and diarrhea to lethargy, seizures, or coma.
How do vets diagnose this condition?
This is usually a retroactive diagnosis after a dog has an adverse reaction to a problem drug--however, genetic testing could help you avoid a first reaction altogether.
How is this condition treated?
MDR1 is perfectly avoidable simply by avoiding the problem drugs, or problem dosages.